To all users on Syneos Health GCP, RMS and Izenda, please note that this system will be decommissioned on 15th October 2022 and will no longer be available for use. Please reach out to for any further questions.
Grant Management System (GMS)

Welcome to the Opioid Analgesic REMS GMS homepage provided by the Opioid Analgesic REMS Program Companies (RPC).

Grant submissions for Request for Application (RFA) 120122 are no longer being accepted.

Important Information for CE providers:

CE providers should reference the approved FDA Opioid Analgesic REMS Education Blueprint for Health Care Providers Involved in the Treatment and Monitoring of Patients with Pain, and are encouraged to reference the MedBiquitous website periodically for updates to the REMS definitions. To learn more about the Opioid Analgesic REMS, please click here. For additional questions regarding grant applications, please reach out to the Grant Coordinator at

The RPC has adopted a policy under which any member or observer company personnel, outside panel members, experts, or other third parties designed to participate in its REMS-compliant accredited continuing education grant application review process are requested to disclose any “conflicts of interest” (as defined by the RPC) relating to applicants seeking RPC-funded grants and/or applicant-identified education partners. In the event that such a conflict of interest is disclosed, the disclosing individual shall refrain from participating in the review of the grant application that is the subject of the conflict of interest is disclosed.

Thank you,